Human mitochondrial carbonic anhydrase: cDNA cloning, expression, subcellular localization, and mapping to chromosome 16.
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چکیده
منابع مشابه
Human mitochondrial carbonic anhydrase: cDNA cloning, expression, subcellular localization, and mapping to chromosome 16.
A full-length cDNA clone encoding human mitochondrial carbonic anhydrase (CA), CA V, was isolated from a human liver cDNA library. The 1123-bp cDNA includes a 55-bp 5' untranslated region, a 915-bp open reading frame, and a 153-bp 3' untranslated region. Expression of the cDNA in COS cells produced active enzyme. The 34-kDa precursor and 30-kDa mature form of CA V were identified on Western blo...
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Carbonic anhydrase (CA, carbonate dehydratase, carbonate hydrolyase; EC 4.2.1.1) is a zinccontaining enzyme that catalyzes the reversible hydration of CO2 (CO2 + H2O HCO3 – + H) (Khalifah, 1971). CA is one of the enzymes whose catalytic velocities are confi rmed to be the fastest. It is widely distributed in animals, plants, archaebacteria and eubacteria (Hewett-Emmett and Tashian, 1996). The k...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1993
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.90.16.7623